Effective and less toxic reversal of low-molecular weight heparin anticoagulation by a designer variant of protamine.

Wakefield, T W

Effective and less toxic reversal of low-molecular weight heparin anticoagulation by a designer variant of protamine. [electronic resource] - Journal of vascular surgery May 1995 - 839-49; discussion 849-50 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

0741-5214

10.1016/s0741-5214(05)80016-3 doi


Amino Acid Sequence
Animals
Blood Coagulation--drug effects
Blood Pressure--drug effects
Cardiac Output--drug effects
Dogs
Drug Design
Drug Interactions
Female
Heart Rate--drug effects
Heparin, Low-Molecular-Weight--metabolism
Injections, Intravenous
Molecular Sequence Data
Molecular Weight
Oxygen Consumption--drug effects
Protamines--chemical synthesis
Protein Binding
Time Factors
Whole Blood Coagulation Time