Characterization of cross-resistance to methotrexate in a human breast cancer cell line selected for resistance to melphalan.

Moscow, J A

Characterization of cross-resistance to methotrexate in a human breast cancer cell line selected for resistance to melphalan. [electronic resource] - Biochemical pharmacology Apr 1995 - 1069-78 p. digital

Publication Type: Comparative Study; Journal Article

0006-2952

10.1016/0006-2952(95)98503-2 doi


Breast Neoplasms--drug therapy
Cell Line--drug effects
Drug Resistance, Multiple
Humans
Melphalan--metabolism
Methotrexate--metabolism
Multienzyme Complexes--analysis
Tetrahydrofolate Dehydrogenase--analysis
Thymidylate Synthase--analysis
Trimetrexate--metabolism