Diminished responsiveness of senescent normal human fibroblasts to TNF-dependent proliferation and interleukin production is not due to its effect on the receptors or on the activation of a nuclear factor NF-kappa B.

Aggarwal, B B

Diminished responsiveness of senescent normal human fibroblasts to TNF-dependent proliferation and interleukin production is not due to its effect on the receptors or on the activation of a nuclear factor NF-kappa B. [electronic resource] - Experimental cell research May 1995 - 381-8 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0014-4827

10.1006/excr.1995.1169 doi


Base Sequence
Binding Sites
Cell Division--drug effects
Cell Nucleus--drug effects
Cells, Cultured
Cellular Senescence
Cytokines--pharmacology
Fibroblast Growth Factor 2--pharmacology
Fibroblasts--cytology
HIV Long Terminal Repeat
Humans
Infant, Newborn
Interleukin-1--pharmacology
Interleukin-6--biosynthesis
Interleukin-8--biosynthesis
Interleukins--biosynthesis
Kinetics
Male
Molecular Sequence Data
NF-kappa B--metabolism
Oligodeoxyribonucleotides
Receptors, Tumor Necrosis Factor--metabolism
Skin--cytology
Tumor Necrosis Factor-alpha--metabolism