Taxol and colchicine increase LPS-induced pro-IL-1 beta production, but do not increase IL-1 beta secretion. A role for microtubules in the regulation of IL-1 beta production.

O'Brien, J M

Taxol and colchicine increase LPS-induced pro-IL-1 beta production, but do not increase IL-1 beta secretion. A role for microtubules in the regulation of IL-1 beta production. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Apr 1995 - 4113-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-1767


Animals
Cattle
Colchicine--administration & dosage
Humans
In Vitro Techniques
Interleukin-1--biosynthesis
Lipopolysaccharides--administration & dosage
Microtubules--physiology
Paclitaxel--administration & dosage
Protein Binding
Protein Precursors--metabolism
Protein Processing, Post-Translational--drug effects
Secretory Rate--drug effects