The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase.

Wilson, J E

The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase. [electronic resource] - Antimicrobial agents and chemotherapy Aug 1993 - 1720-2 p. digital

Publication Type: Journal Article

0066-4804

10.1128/AAC.37.8.1720 doi


Antiviral Agents--pharmacology
Cytidine Triphosphate--analogs & derivatives
DNA, Viral--biosynthesis
Emtricitabine--analogs & derivatives
HIV Reverse Transcriptase
HIV-1--drug effects
Kinetics
RNA, Viral--biosynthesis
Reverse Transcriptase Inhibitors
Stereoisomerism
Thiophenes
Zalcitabine--analogs & derivatives