In vivo anti-leukemic efficacy of anti-CD7-pokeweed antiviral protein immunotoxin against human T-lineage acute lymphoblastic leukemia/lymphoma in mice with severe combined immunodeficiency.

Gunther, R

In vivo anti-leukemic efficacy of anti-CD7-pokeweed antiviral protein immunotoxin against human T-lineage acute lymphoblastic leukemia/lymphoma in mice with severe combined immunodeficiency. [electronic resource] - Leukemia Feb 1993 - 298-309 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0887-6924


Animals
Antibodies, Monoclonal--therapeutic use
Antigens, CD--immunology
Antigens, CD7
Antigens, Differentiation, T-Lymphocyte--immunology
Antineoplastic Agents, Phytogenic--therapeutic use
Base Sequence
Drug Screening Assays, Antitumor
Humans
Immunotoxins--therapeutic use
Leukemic Infiltration
Lymphoma--pathology
Mice
Mice, SCID
Molecular Sequence Data
N-Glycosyl Hydrolases
Neoplasm Transplantation
Oligonucleotide Probes
Plant Proteins--therapeutic use
Polymerase Chain Reaction
Precursor Cell Lymphoblastic Leukemia-Lymphoma--pathology
Ribosome Inactivating Proteins, Type 1
Specific Pathogen-Free Organisms
Tumor Cells, Cultured