Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor bis(maltolato)oxovanadium(IV).

Schieven, G L

Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor bis(maltolato)oxovanadium(IV). [electronic resource] - The Journal of biological chemistry Sep 1995 - 20824-31 p. digital

Publication Type: Comparative Study; Journal Article

0021-9258

10.1074/jbc.270.35.20824 doi


Animals
Apoptosis--drug effects
B-Lymphocytes--cytology
Calcium--metabolism
Cell Line
Cytoplasm--metabolism
Dose-Response Relationship, Drug
Humans
Hypoglycemic Agents--pharmacology
Immunoglobulin M--physiology
Kinetics
Leukemia, Promyelocytic, Acute
Leukemia, T-Cell
Lymphocyte Activation
Lymphoma, B-Cell
Mice
Phospholipases--metabolism
Phytohemagglutinins
Protein Tyrosine Phosphatases--antagonists & inhibitors
Protein-Tyrosine Kinases--metabolism
Proteins--metabolism
Pyrones--pharmacology
Receptors, Antigen, B-Cell--drug effects
Receptors, Antigen, T-Cell--drug effects
Receptors, Interleukin-2--biosynthesis
Signal Transduction--drug effects
TYK2 Kinase
Tumor Cells, Cultured
Vanadates--pharmacology