5,7-dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-6H- pyrrolo[3,2-f]-1,2-benzisoxazol-6-one: a potent and centrally-selective inhibitor of acetylcholinesterase with an improved margin of safety.
Villalobos, A
5,7-dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-6H- pyrrolo[3,2-f]-1,2-benzisoxazol-6-one: a potent and centrally-selective inhibitor of acetylcholinesterase with an improved margin of safety. [electronic resource] - Journal of medicinal chemistry Jul 1995 - 2802-8 p. digital
Publication Type: Comparative Study; Journal Article
0022-2623
10.1021/jm00015a002 doi
Animals
Butyrylcholinesterase
Cholinesterase Inhibitors--chemical synthesis
Isoxazoles--chemical synthesis
Male
Piperidines--chemical synthesis
Rats
Rats, Sprague-Dawley
Structure-Activity Relationship
Tacrine--pharmacology
5,7-dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-6H- pyrrolo[3,2-f]-1,2-benzisoxazol-6-one: a potent and centrally-selective inhibitor of acetylcholinesterase with an improved margin of safety. [electronic resource] - Journal of medicinal chemistry Jul 1995 - 2802-8 p. digital
Publication Type: Comparative Study; Journal Article
0022-2623
10.1021/jm00015a002 doi
Animals
Butyrylcholinesterase
Cholinesterase Inhibitors--chemical synthesis
Isoxazoles--chemical synthesis
Male
Piperidines--chemical synthesis
Rats
Rats, Sprague-Dawley
Structure-Activity Relationship
Tacrine--pharmacology