Beneficial effects of the phosphodiesterase inhibitors BRL 61063, pentoxifylline, and rolipram in a murine model of endotoxin shock.

Badger, A M

Beneficial effects of the phosphodiesterase inhibitors BRL 61063, pentoxifylline, and rolipram in a murine model of endotoxin shock. [electronic resource] - Circulatory shock Dec 1994 - 188-95 p. digital

Publication Type: Journal Article

0092-6213


3',5'-Cyclic-AMP Phosphodiesterases
Animals
Cells, Cultured
Cyclic Nucleotide Phosphodiesterases, Type 4
Disease Models, Animal
Macrophages, Peritoneal--drug effects
Male
Mice
Mice, Inbred C57BL
Pentoxifylline--therapeutic use
Phosphodiesterase Inhibitors--therapeutic use
Phosphoric Diester Hydrolases--metabolism
Pyrrolidinones--therapeutic use
Rolipram
Shock, Septic--drug therapy
Tumor Necrosis Factor-alpha--antagonists & inhibitors
Xanthines--therapeutic use