TNF-alpha production as an in vitro assay predictive of cytokine-mediated toxic reactions induced by monoclonal antibodies.

Robinet, E

TNF-alpha production as an in vitro assay predictive of cytokine-mediated toxic reactions induced by monoclonal antibodies. [electronic resource] - Toxicology Jun 1995 - 213-23 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0300-483X

10.1016/0300-483x(95)03094-v doi


Antibodies, Monoclonal--toxicity
CD3 Complex--immunology
CD4 Antigens--immunology
Cells, Cultured
Enzyme-Linked Immunosorbent Assay
Humans
In Vitro Techniques
Kinetics
Leukocytes, Mononuclear--cytology
Lipopolysaccharides--toxicity
Tumor Necrosis Factor-alpha--biosynthesis