Intrathymic transplantation of islet antigen affects CD8+ diabetogenic T-cells resulting in tolerance to autoimmune IDDM.

Baumann, E E

Intrathymic transplantation of islet antigen affects CD8+ diabetogenic T-cells resulting in tolerance to autoimmune IDDM. [electronic resource] - Diabetes Aug 1995 - 871-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0012-1797

10.2337/diab.44.8.871 doi


Animals
Antibodies, Monoclonal--administration & dosage
CD3 Complex--analysis
CD4-Positive T-Lymphocytes--immunology
CD8-Positive T-Lymphocytes--immunology
Diabetes Mellitus, Experimental--immunology
Diabetes Mellitus, Type 1--immunology
Flow Cytometry
Immune Tolerance
Islets of Langerhans--drug effects
Islets of Langerhans Transplantation--immunology
Lymphocyte Depletion
Male
Mice
Mice, Inbred C57BL
Spleen--immunology
Streptozocin--pharmacology
T-Lymphocytes--immunology
Thymectomy
Thymus Gland
Transplantation, Heterotopic