Profile of procarbazine-induced embryotoxicity in an embryo hepatocyte co-culture system and after in utero glutathione depletion.

Ebron-McCoy, M T

Profile of procarbazine-induced embryotoxicity in an embryo hepatocyte co-culture system and after in utero glutathione depletion. [electronic resource] - Teratogenesis, carcinogenesis, and mutagenesis 1995 - 33-42 p. digital

Publication Type: Journal Article

0270-3211

10.1002/tcm.1770150105 doi


Abnormalities, Drug-Induced--etiology
Animals
Antimetabolites--toxicity
Biotransformation
Buthionine Sulfoximine
Cells, Cultured
Embryo, Mammalian--drug effects
Embryonic and Fetal Development--drug effects
Female
Glutathione--metabolism
Ketones--toxicity
Liver--cytology
Male
Methionine Sulfoximine--analogs & derivatives
Organ Culture Techniques
Pregnancy
Procarbazine--blood
Rats
Rats, Sprague-Dawley
Time Factors