Anti-tumour effects of an antibody-carboxypeptidase G2 conjugate in combination with phenol mustard prodrugs.

Blakey, D C

Anti-tumour effects of an antibody-carboxypeptidase G2 conjugate in combination with phenol mustard prodrugs. [electronic resource] - British journal of cancer Nov 1995 - 1083-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0007-0920

10.1038/bjc.1995.469 doi


Aniline Mustard--analogs & derivatives
Animals
Antibodies, Monoclonal--administration & dosage
Antibodies, Neoplasm--administration & dosage
Antineoplastic Agents, Alkylating--pharmacokinetics
Bacterial Proteins--administration & dosage
Biotransformation
Carcinoembryonic Antigen--immunology
Colorectal Neoplasms--drug therapy
Drug Screening Assays, Antitumor
Female
Humans
Immunoconjugates--therapeutic use
Immunoglobulin Fab Fragments--administration & dosage
Mice
Mice, Nude
Neoplasm Transplantation
Prodrugs--pharmacokinetics
Pseudomonas--enzymology
Substrate Specificity
Tumor Cells, Cultured
gamma-Glutamyl Hydrolase--administration & dosage