Dexamethasone enhances insulin-like growth factor-I effects on skeletal muscle cell proliferation. Role of specific intracellular signaling pathways.

Giorgino, F

Dexamethasone enhances insulin-like growth factor-I effects on skeletal muscle cell proliferation. Role of specific intracellular signaling pathways. [electronic resource] - The Journal of clinical investigation Sep 1995 - 1473-83 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9738

10.1172/JCI118184 doi


Animals
Blotting, Northern
Cell Division--drug effects
Cell Line
DNA--biosynthesis
Dexamethasone--pharmacology
Drug Synergism
Gene Expression--drug effects
Insulin Receptor Substrate Proteins
Insulin-Like Growth Factor I--biosynthesis
Insulin-Like Growth Factor II--biosynthesis
Muscle, Skeletal--cytology
Phosphatidylinositol 3-Kinases
Phosphoproteins--biosynthesis
Phosphorylation
Phosphotransferases (Alcohol Group Acceptor)--biosynthesis
Phosphotyrosine
Proto-Oncogene Proteins c-fos--biosynthesis
Rats
Receptor Protein-Tyrosine Kinases--metabolism
Receptor, IGF Type 1--biosynthesis
Signal Transduction
Tyrosine--analogs & derivatives