The beta-endorphin inhibition of mitogen-induced splenocytes proliferation is mediated by central and peripheral paracrine/autocrine effects of the opioid.

Panerai, A E

The beta-endorphin inhibition of mitogen-induced splenocytes proliferation is mediated by central and peripheral paracrine/autocrine effects of the opioid. [electronic resource] - Journal of neuroimmunology Apr 1995 - 71-6 p. digital

Publication Type: Comparative Study; Journal Article

0165-5728

10.1016/0165-5728(94)00189-u doi


Analysis of Variance
Animals
Cerebral Ventricles--drug effects
Hypophysectomy
Injections, Intraperitoneal
Injections, Intraventricular
Lymphocyte Activation--drug effects
Male
Naloxone--administration & dosage
Phytohemagglutinins
Rats
Rats, Sprague-Dawley
Spleen--drug effects
T-Lymphocytes--drug effects
beta-Endorphin--administration & dosage
gamma-Globulins--administration & dosage