Synthesis, hydrolytic behavior, and anti-HIV activity of selected acyloxyalkyl esters of trisodium phosphonoformate (foscarnet sodium).

Iyer, R P

Synthesis, hydrolytic behavior, and anti-HIV activity of selected acyloxyalkyl esters of trisodium phosphonoformate (foscarnet sodium). [electronic resource] - Journal of pharmaceutical sciences Sep 1994 - 1269-73 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-3549

10.1002/jps.2600830916 doi


Antiviral Agents--chemical synthesis
Cell Line
Cytopathogenic Effect, Viral--drug effects
Foscarnet--analogs & derivatives
HIV Reverse Transcriptase
HIV-1--drug effects
Humans
Hydrolysis
Magnetic Resonance Spectroscopy
Prodrugs--chemical synthesis
Reverse Transcriptase Inhibitors