Mobile ionophores are a novel class of P-glycoprotein inhibitors. The effects of ionophores on 4'-O-tetrahydropyranyl-adriamycin incorporation in K562 drug-resistant cells.

Borrel, M N

Mobile ionophores are a novel class of P-glycoprotein inhibitors. The effects of ionophores on 4'-O-tetrahydropyranyl-adriamycin incorporation in K562 drug-resistant cells. [electronic resource] - European journal of biochemistry Jul 1994 - 125-33 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-2956

10.1111/j.1432-1033.1994.tb18973.x doi


ATP Binding Cassette Transporter, Subfamily B, Member 1
Adenosine Triphosphate--metabolism
Anti-Bacterial Agents--pharmacology
Antibiotics, Antineoplastic--pharmacology
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone--pharmacology
Carrier Proteins--antagonists & inhibitors
Cell Division--drug effects
Cyclosporine--pharmacology
Doxorubicin--analogs & derivatives
Drug Resistance
Gramicidin--pharmacology
Humans
Ionophores--pharmacology
Macrolides
Membrane Glycoproteins--antagonists & inhibitors
Membrane Potentials
Tumor Cells, Cultured
Valinomycin--pharmacology