A structure-activity analysis of antagonism of the growth factor and angiogenic activity of basic fibroblast growth factor by suramin and related polyanions.

Braddock, P S

A structure-activity analysis of antagonism of the growth factor and angiogenic activity of basic fibroblast growth factor by suramin and related polyanions. [electronic resource] - British journal of cancer May 1994 - 890-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0007-0920

10.1038/bjc.1994.172 doi


Animals
Capillaries
Cattle
Cell Division--drug effects
Cells, Cultured
Dose-Response Relationship, Drug
Endothelium, Vascular--cytology
Female
Fibroblast Growth Factor 2--antagonists & inhibitors
Inflammation--metabolism
Male
Mice
Mice, Inbred C3H
Neovascularization, Pathologic--prevention & control
Pentosan Sulfuric Polyester--pharmacology
Rats
Rats, Wistar
Structure-Activity Relationship
Suramin--analogs & derivatives
Thymidine--analogs & derivatives