Effects of MKS-492 on antigen-induced bronchoconstriction and allergic reaction in guinea pigs and rats.

Nagai, H

Effects of MKS-492 on antigen-induced bronchoconstriction and allergic reaction in guinea pigs and rats. [electronic resource] - Japanese journal of pharmacology Dec 1993 - 405-13 p. digital

Publication Type: Comparative Study; Journal Article

0021-5198

10.1254/jjp.63.405 doi


Aminophylline--pharmacology
Animals
Antigens--immunology
Bronchial Hyperreactivity--drug therapy
Bronchoalveolar Lavage Fluid--cytology
Bronchoconstriction--drug effects
Female
Guinea Pigs
Histamine--pharmacology
Histamine Release
Hypersensitivity--drug therapy
Leukocyte Count--drug effects
Leukotriene B4--pharmacology
Male
Muscle Relaxation--drug effects
Muscle, Smooth--drug effects
Passive Cutaneous Anaphylaxis--drug effects
Phosphodiesterase Inhibitors--pharmacology
Platelet Activating Factor--toxicity
Purinones--pharmacology
Rats
Rats, Wistar
Superoxides--metabolism
Trachea--drug effects