Properties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts.

Haber, D A

Properties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts. [electronic resource] - The Journal of biological chemistry Sep 1981 - 9501-10 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258


Animals
Cell Line
Drug Stability
Embryo, Mammalian
Fibroblasts--enzymology
Folic Acid Antagonists--pharmacology
Gene Amplification--drug effects
Hydrogen-Ion Concentration
Kinetics
Methotrexate--metabolism
Mice
Tetrahydrofolate Dehydrogenase--genetics