Metabolic activation of acetylenes. Covalent binding of [1,2-14C]octyne to protein, DNA and haem in vitro and the protective effects of certain thiol compounds.

White, I N

Metabolic activation of acetylenes. Covalent binding of [1,2-14C]octyne to protein, DNA and haem in vitro and the protective effects of certain thiol compounds. [electronic resource] - The Biochemical journal May 1984 - 85-94 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0264-6021

10.1042/bj2200085 doi


Acetylcysteine--chemical synthesis
Alkynes--chemical synthesis
Animals
Chromatography, High Pressure Liquid
DNA--metabolism
Heme--metabolism
In Vitro Techniques
Magnetic Resonance Spectroscopy
Male
Microsomes, Liver--metabolism
Protein Binding
Proteins--metabolism
Rats
Sulfhydryl Compounds--pharmacology