A novel opioid receptor site directed alkylating agent with irreversible narcotic antagonistic and reversible agonistic activities.

Portoghese, P S

A novel opioid receptor site directed alkylating agent with irreversible narcotic antagonistic and reversible agonistic activities. [electronic resource] - Journal of medicinal chemistry Mar 1980 - 233-4 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-2623

10.1021/jm00177a002 doi


Alkylating Agents--chemical synthesis
Animals
Guinea Pigs
In Vitro Techniques
Morphinans--chemical synthesis
Muscle Contraction--drug effects
Muscle, Smooth--drug effects
Naltrexone--analogs & derivatives
Narcotic Antagonists--chemical synthesis
Narcotics--chemical synthesis
Oxymorphone--analogs & derivatives
Receptors, Opioid--drug effects