Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity.

Cooney, D A

Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity. [electronic resource] - Advances in enzyme regulation 1983 - 271-303 p. digital

Publication Type: Journal Article

0065-2571

10.1016/0065-2571(83)90019-5 doi


Animals
Cell Survival--drug effects
Cells, Cultured
Dose-Response Relationship, Drug
Guanosine Triphosphate--metabolism
IMP Dehydrogenase--antagonists & inhibitors
Ketone Oxidoreductases--antagonists & inhibitors
Magnetic Resonance Spectroscopy
Mass Spectrometry
Mice
NAD--analogs & derivatives
Ribavirin--analogs & derivatives
Ribonucleosides--pharmacology
Spectrophotometry