Synthesis and CNS activity of 3-substituted 7-chloro-5-phenyl-1,3,4-benzotriazepin-2-ones.

Kohl, H

Synthesis and CNS activity of 3-substituted 7-chloro-5-phenyl-1,3,4-benzotriazepin-2-ones. [electronic resource] - Journal of pharmaceutical sciences Jun 1974 - 838-41 p. digital

Publication Type: Comparative Study; Journal Article

0022-3549

10.1002/jps.2600630606 doi


Alkylation
Animals
Anticonvulsants--pharmacology
Behavior, Animal--drug effects
Benzazepines--chemical synthesis
Central Nervous System--drug effects
Chlordiazepoxide--pharmacology
Cricetinae
Cyclization
Depression, Chemical
Diazepam--pharmacology
Drug Synergism
Electroshock
Exploratory Behavior--drug effects
Hexobarbital--pharmacology
Hypnotics and Sedatives--pharmacology
Lethal Dose 50
Mass Spectrometry
Methamphetamine--antagonists & inhibitors
Mice
Motor Activity--drug effects
Muscle Tonus--drug effects
Pentylenetetrazole--antagonists & inhibitors
Reflex--drug effects
Sleep--drug effects