Purification of IMP:pyrophosphate phosphoribosyltransferases, catalytically incompetent enzymes in Lesch-Nyhan disease.

Rubin, C S

Purification of IMP:pyrophosphate phosphoribosyltransferases, catalytically incompetent enzymes in Lesch-Nyhan disease. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jul 1971 - 1461-4 p. digital

Publication Type: Journal Article

0027-8424

10.1073/pnas.68.7.1461 doi


Adenine Nucleotides
Animals
Athetosis--enzymology
Carbon Isotopes
Chemical Precipitation
Chromatography, DEAE-Cellulose
Chromatography, Gel
Cross Reactions
Diphosphates
Drug Stability
Electrophoresis, Disc
Erythrocytes--enzymology
Genes
Hot Temperature
Humans
Hypoxanthines
Immune Sera--isolation & purification
Infant
Intellectual Disability--enzymology
Isoenzymes--isolation & purification
Lesch-Nyhan Syndrome--blood
Mutation
Neutralization Tests
Nucleotides
Pentosephosphates
Purine-Pyrimidine Metabolism, Inborn Errors--enzymology
Quaternary Ammonium Compounds
Rabbits
Rats
Self Mutilation--enzymology
Sulfates
Transferases--blood