D-(R)- and L-(S)-3-alkylaminopyrrolidino-substituted dihydrodibenzo (b,f)- and-(b,e)thiepins, xanthenes, and diphenylmethanes.

Witiak, D T

D-(R)- and L-(S)-3-alkylaminopyrrolidino-substituted dihydrodibenzo (b,f)- and-(b,e)thiepins, xanthenes, and diphenylmethanes. [electronic resource] - Journal of medicinal chemistry Jul 1974 - 690-6 p. digital

Publication Type: Journal Article

0022-2623

10.1021/jm00253a007 doi


Animals
Antiparkinson Agents--pharmacology
Barbiturates--pharmacology
Benzene Derivatives--chemical synthesis
Blood Pressure--drug effects
Body Temperature--drug effects
Dibenzothiepins--chemical synthesis
Drug Synergism
Female
Guinea Pigs
Histamine H1 Antagonists--pharmacology
Lethal Dose 50
Male
Mice
Mice, Inbred ICR
Optical Rotation
Oxotremorine--toxicity
Parasympatholytics--pharmacology
Pyrrolidines--pharmacology
Rats
Serotonin Antagonists
Sleep--drug effects
Structure-Activity Relationship
Xanthenes--chemical synthesis