Dissociation of antitumor potency from anthracycline cardiotoxicity in a doxorubicin analog.

Sikic, B I

Dissociation of antitumor potency from anthracycline cardiotoxicity in a doxorubicin analog. [electronic resource] - Science (New York, N.Y.) Jun 1985 - 1544-6 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0036-8075

10.1126/science.4012308 doi


Animals
Antineoplastic Agents
Breast Neoplasms--drug therapy
Cell Line
Chemical Phenomena
Chemistry
Dose-Response Relationship, Drug
Doxorubicin--adverse effects
Female
Heart--drug effects
Humans
Isoenzymes
L-Lactate Dehydrogenase--analysis
Mice
Myocardium--enzymology
Ovarian Neoplasms--drug therapy
Pregnancy