Topically applied nitropyrenes are potent inducers of cutaneous and hepatic monooxygenases.

Asokan, P

Topically applied nitropyrenes are potent inducers of cutaneous and hepatic monooxygenases. [electronic resource] - Biochemical and biophysical research communications May 1985 - 134-40 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0006-291X

10.1016/0006-291x(85)91413-5 doi


7-Alkoxycoumarin O-Dealkylase
Animals
Aryl Hydrocarbon Hydroxylases--biosynthesis
Cytochrome P-450 CYP1A1
Cytochrome P-450 Enzyme System
Enzyme Induction
Epoxide Hydrolases--biosynthesis
Female
Microsomes, Liver--drug effects
Oxidoreductases--biosynthesis
Oxygenases--biosynthesis
Pregnancy
Pyrenes--pharmacology
Rats
Skin--drug effects
Spectrophotometry
Time Factors