Identification of potential antiatherosclerotic/hypolipidemic agents by their effect on hepatic conversion of androst-4-ene-3,17-dione to etiocholanolone and androsterone.

Wasvary, M J

Identification of potential antiatherosclerotic/hypolipidemic agents by their effect on hepatic conversion of androst-4-ene-3,17-dione to etiocholanolone and androsterone. [electronic resource] - Atherosclerosis Jan 1985 - 23-36 p. digital

Publication Type: Journal Article

0021-9150

10.1016/0021-9150(85)90150-9 doi


3-Hydroxysteroid Dehydrogenases--metabolism
3-Oxo-5-alpha-Steroid 4-Dehydrogenase--metabolism
3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)
Androstenedione--metabolism
Androsterone--biosynthesis
Animals
Arteriosclerosis--drug therapy
Bile--metabolism
Cytosol--enzymology
Etiocholanolone--biosynthesis
Female
Hypolipidemic Agents--pharmacology
Hypophysectomy
Liver--drug effects
Microsomes, Liver--enzymology
Oxidoreductases--metabolism
Rats