Pharmacokinetics of the thymidylate synthase inhibitor N10-propargyl-5,8-dideazafolic acid (CB3717) in the mouse.

Newell, D R

Pharmacokinetics of the thymidylate synthase inhibitor N10-propargyl-5,8-dideazafolic acid (CB3717) in the mouse. [electronic resource] - Cancer treatment reports Aug 1986 - 971-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0361-5960


Animals
Cecum--metabolism
Chromatography, High Pressure Liquid
Feces--analysis
Folic Acid--analogs & derivatives
Kinetics
Male
Mass Spectrometry
Mice
Mice, Inbred C57BL
Protein Binding
Quinazolines--blood
Scintillation Counting
Thymidylate Synthase--antagonists & inhibitors
Tissue Distribution