Estimation of the elimination half-life of a drug at any serum concentration when the Km and Vmax of the drug are known: calculations and validation with phenytoin.

Browne, T R

Estimation of the elimination half-life of a drug at any serum concentration when the Km and Vmax of the drug are known: calculations and validation with phenytoin. [electronic resource] - Journal of clinical pharmacology Apr 1987 - 318-20 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0091-2700

10.1002/j.1552-4604.1987.tb03022.x doi


Half-Life
Humans
Models, Biological
Phenytoin--blood