Stereochemistry of the functional group determines the mechanism of aromatase inhibition by 6-bromoandrostenedione.

Osawa, Y

Stereochemistry of the functional group determines the mechanism of aromatase inhibition by 6-bromoandrostenedione. [electronic resource] - Endocrinology Sep 1987 - 1010-6 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0013-7227

10.1210/endo-121-3-1010 doi


Androstenedione--analogs & derivatives
Animals
Aromatase Inhibitors
Binding, Competitive
Female
Humans
Kinetics
Male
Microsomes, Liver--enzymology
Molecular Conformation
NADP--pharmacology
Placenta--enzymology
Pregnancy
Rabbits
Rats
Rats, Inbred Strains
Structure-Activity Relationship