Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing.

Honegger, A M

Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing. [electronic resource] - Cell Oct 1987 - 199-209 p. digital

Publication Type: Journal Article

0092-8674

10.1016/0092-8674(87)90147-4 doi


Adenosine Triphosphate--metabolism
Binding Sites
Cell Line
Epidermal Growth Factor--pharmacokinetics
ErbB Receptors--drug effects
Humans
Mutation
Protein-Tyrosine Kinases--metabolism