Studies on the vasoocclusive crisis of sickle cell disease. III. In vitro and in vivo effect of the pyrimido-pyrimidine derivative, RA-233: studies on its mechanism of action.

Ambrus, J L

Studies on the vasoocclusive crisis of sickle cell disease. III. In vitro and in vivo effect of the pyrimido-pyrimidine derivative, RA-233: studies on its mechanism of action. [electronic resource] - Journal of medicine 1987 - 165-98 p. digital

Publication Type: Journal Article

0025-7850


Adult
Anemia, Sickle Cell--blood
Animals
Antisickling Agents--pharmacology
Child
Child, Preschool
Erythrocyte Deformability--drug effects
Female
Genotype
Humans
Macaca
Male
Mopidamol--pharmacology
Osmotic Fragility--drug effects
Platelet Aggregation--drug effects
Potassium--metabolism
Pyrimidines--therapeutic use