The contribution of O6-methylguanine and methylphosphotriesters to the cytotoxicity of alkylating agents in mammalian cells.

Hall, J

The contribution of O6-methylguanine and methylphosphotriesters to the cytotoxicity of alkylating agents in mammalian cells. [electronic resource] - Carcinogenesis Sep 1988 - 1587-93 p. digital

Publication Type: Journal Article

0143-3334

10.1093/carcin/9.9.1587 doi


Alkylating Agents--toxicity
Animals
Cell Line
Cloning, Molecular
Cricetinae
DNA Damage
DNA Repair
Drug Resistance
Guanine--analogs & derivatives
Methyl Methanesulfonate
Methylation
Methylnitronitrosoguanidine
Methyltransferases--genetics
O(6)-Methylguanine-DNA Methyltransferase
Organophosphates--metabolism
Organophosphorus Compounds--metabolism
Structure-Activity Relationship
Transfection