Synthesis, molecular modeling, DNA binding, and antitumor properties of some substituted amidoanthraquinones.

Collier, D A

Synthesis, molecular modeling, DNA binding, and antitumor properties of some substituted amidoanthraquinones. [electronic resource] - Journal of medicinal chemistry Apr 1988 - 847-57 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm00399a028 doi


Animals
Anthraquinones--chemical synthesis
Antineoplastic Agents--pharmacology
Cattle
Computer Simulation
Crystallography
DNA--metabolism
DNA, Circular--metabolism
Leukemia L1210--pathology
Models, Molecular
Sarcoma 180--pathology
Solutions
Structure-Activity Relationship
Tumor Cells, Cultured--drug effects