Purification and characterization of a liver microsomal cytochrome P-450 isoenzyme with a high affinity and metabolic capacity for coumarin from pyrazole-treated D2 mice.

Juvonen, R O

Purification and characterization of a liver microsomal cytochrome P-450 isoenzyme with a high affinity and metabolic capacity for coumarin from pyrazole-treated D2 mice. [electronic resource] - European journal of biochemistry Jan 1988 - 205-11 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-2956

10.1111/j.1432-1033.1988.tb13777.x doi


Animals
Aryl Hydrocarbon Hydroxylases
Chromatography
Coumarins--metabolism
Cytochrome P-450 CYP2A6
Cytochrome P-450 Enzyme System--isolation & purification
Hydrogen-Ion Concentration
Isoenzymes--isolation & purification
Kinetics
Mice
Microsomes, Liver--enzymology
Mixed Function Oxygenases--isolation & purification
Molecular Weight
Phospholipids--metabolism
Pyrazoles--pharmacology
Spectrum Analysis
Substrate Specificity