Mechanism-based isocoumarin inhibitors for trypsin and blood coagulation serine proteases: new anticoagulants.

Kam, C M

Mechanism-based isocoumarin inhibitors for trypsin and blood coagulation serine proteases: new anticoagulants. [electronic resource] - Biochemistry Apr 1988 - 2547-57 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0006-2960

10.1021/bi00407a042 doi


Animals
Anticoagulants
Blood Coagulation Factors--antagonists & inhibitors
Cattle
Coumarins--pharmacology
Female
Humans
Kinetics
Placenta--enzymology
Pregnancy
Prekallikrein--antagonists & inhibitors
Serine Endopeptidases--blood
Serine Proteinase Inhibitors
Spectrometry, Fluorescence
Structure-Activity Relationship
Trypsin Inhibitors--pharmacology