Allosteric properties of the 5-HT2 receptor system of the rat tail artery. Ritanserin and methysergide are not competitive 5-HT2 receptor antagonists but allosteric modulators.

Frenken, M

Allosteric properties of the 5-HT2 receptor system of the rat tail artery. Ritanserin and methysergide are not competitive 5-HT2 receptor antagonists but allosteric modulators. [electronic resource] - Naunyn-Schmiedeberg's archives of pharmacology Apr 1987 - 359-66 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0028-1298

10.1007/BF00165548 doi


Allosteric Regulation
Animals
Arteries--metabolism
Binding, Competitive
In Vitro Techniques
Male
Methysergide--pharmacology
Muscle, Smooth, Vascular--metabolism
Piperidines--pharmacology
Rats
Rats, Inbred Strains
Receptors, Serotonin--metabolism
Regional Blood Flow--drug effects
Ritanserin
Tail--blood supply