Synergistic inhibition of polyamine synthesis and growth by difluoromethylornithine plus methylthioadenosine in methylthioadenosine phosphorylase-deficient murine lymphoma cells.

Yamanaka, H

Synergistic inhibition of polyamine synthesis and growth by difluoromethylornithine plus methylthioadenosine in methylthioadenosine phosphorylase-deficient murine lymphoma cells. [electronic resource] - Cancer research Apr 1987 - 1771-4 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0008-5472


Adenosine--analogs & derivatives
Animals
Cell Division--drug effects
Cell Line
Deoxyadenosines
Drug Synergism
Eflornithine--pharmacology
Kinetics
Lymphoma--metabolism
Mice
Pentosyltransferases--deficiency
Polyamines--antagonists & inhibitors
Purine-Nucleoside Phosphorylase--deficiency
Putrescine--metabolism
Spermidine--metabolism
Spermine--metabolism
Thionucleosides--pharmacology