HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.

Kogler, Melanie

HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases. [electronic resource] - Cancer research 07 2020 - 3009-3022 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1538-7445

10.1158/0008-5472.CAN-19-2270 doi


Animals
Apoptosis
Biomarkers, Tumor--genetics
Carcinogenesis--metabolism
Cell Proliferation
Gene Expression Regulation, Neoplastic
Humans
Lung Neoplasms--etiology
Mice
Mice, Inbred C57BL
Mice, Knockout
Prognosis
Tumor Cells, Cultured
Tumor Suppressor Proteins--genetics
Ubiquitin-Protein Ligases--genetics
Ubiquitination
rac GTP-Binding Proteins--antagonists & inhibitors
rac1 GTP-Binding Protein--antagonists & inhibitors
RAC2 GTP-Binding Protein