Lycopene prevents carcinogen-induced cutaneous tumor by enhancing activation of the Nrf2 pathway through p62-triggered autophagic Keap1 degradation.

Wang, Siliang

Lycopene prevents carcinogen-induced cutaneous tumor by enhancing activation of the Nrf2 pathway through p62-triggered autophagic Keap1 degradation. [electronic resource] - Aging 05 2020 - 8167-8190 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1945-4589

10.18632/aging.103132 doi


Animals
Anticarcinogenic Agents--pharmacology
Autophagy
Gene Expression Regulation, Neoplastic
Kelch-Like ECH-Associated Protein 1--biosynthesis
Lycopene--pharmacology
Mice
NF-E2-Related Factor 2--biosynthesis
RNA, Neoplasm--genetics
Signal Transduction--drug effects
Skin Neoplasms--genetics