Loss of calpains-1 and -2 prevents repair of plasma membrane scrape injuries, but not small pores, and induces a severe muscular dystrophy.

Piper, Ann-Katrin

Loss of calpains-1 and -2 prevents repair of plasma membrane scrape injuries, but not small pores, and induces a severe muscular dystrophy. [electronic resource] - American journal of physiology. Cell physiology 06 2020 - C1226-C1237 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1522-1563

10.1152/ajpcell.00408.2019 doi


Animals
Bacterial Proteins--pharmacology
Calcium Signaling
Calpain--deficiency
Cell Membrane--drug effects
Disease Models, Animal
Dysferlin--deficiency
Female
HEK293 Cells
Humans
Male
Mice, Knockout
Muscle, Skeletal--enzymology
Muscular Dystrophies, Limb-Girdle--enzymology
Muscular Dystrophy, Animal--enzymology
Saponins--pharmacology
Severity of Illness Index
Streptolysins--pharmacology