Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management.
Heringa, Minne B
Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management. [electronic resource] - Regulatory toxicology and pharmacology : RTP Jul 2020 - 104659 p. digital
Publication Type: Journal Article
1096-0295
10.1016/j.yrtph.2020.104659 doi
Dose-Response Relationship, Drug
European Union
Hazardous Substances--administration & dosage
Humans
Kinetics
Risk Management
Toxicity Tests
Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management. [electronic resource] - Regulatory toxicology and pharmacology : RTP Jul 2020 - 104659 p. digital
Publication Type: Journal Article
1096-0295
10.1016/j.yrtph.2020.104659 doi
Dose-Response Relationship, Drug
European Union
Hazardous Substances--administration & dosage
Humans
Kinetics
Risk Management
Toxicity Tests