Impact of DNA Damage Response and Repair (DDR) Gene Mutations on Efficacy of PD-(L)1 Immune Checkpoint Inhibition in Non-Small Cell Lung Cancer.

Ricciuti, Biagio

Impact of DNA Damage Response and Repair (DDR) Gene Mutations on Efficacy of PD-(L)1 Immune Checkpoint Inhibition in Non-Small Cell Lung Cancer. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research 08 2020 - 4135-4142 p. digital

Publication Type: Journal Article; Observational Study; Research Support, Non-U.S. Gov't

1557-3265

10.1158/1078-0432.CCR-19-3529 doi


Adult
Aged
Aged, 80 and over
B7-H1 Antigen--antagonists & inhibitors
Biomarkers, Tumor--genetics
Carcinoma, Non-Small-Cell Lung--drug therapy
DNA Damage
DNA Mutational Analysis
DNA Repair
Drug Resistance, Neoplasm--genetics
Female
Follow-Up Studies
High-Throughput Nucleotide Sequencing
Humans
Immune Checkpoint Inhibitors--pharmacology
Lung--pathology
Lung Neoplasms--drug therapy
Male
Middle Aged
Mutation
Progression-Free Survival
Retrospective Studies