Facts, Patterns, and Principles in Drug Discovery: Appraising the Rule of 5 with Measured Physicochemical Data.

Tinworth, Christopher P

Facts, Patterns, and Principles in Drug Discovery: Appraising the Rule of 5 with Measured Physicochemical Data. [electronic resource] - Journal of medicinal chemistry 09 2020 - 10091-10108 p. digital

Publication Type: Journal Article

1520-4804

10.1021/acs.jmedchem.9b01596 doi


Cell Membrane Permeability
Drug Discovery
Hydrogen Bonding
Hydrophobic and Hydrophilic Interactions
Molecular Weight
Pharmaceutical Preparations--chemistry
Pliability
Solubility