Effects of alkyl phosphorothioates on the hepatic microsomal mixed-function oxidase system in rats. Inhibition of drug-metabolizing enzyme activity and selective increase of NADPH-cytochrome c reductase activity.
Furukawa, N
Effects of alkyl phosphorothioates on the hepatic microsomal mixed-function oxidase system in rats. Inhibition of drug-metabolizing enzyme activity and selective increase of NADPH-cytochrome c reductase activity. [electronic resource] - Biochemical pharmacology Mar 1986 - 1019-26 p. digital
Publication Type: Journal Article
0006-2952
10.1016/0006-2952(86)90093-6 doi
Animals
Cholinesterase Inhibitors--toxicity
Dose-Response Relationship, Drug
Male
Methylcholanthrene--pharmacology
Microsomes, Liver--drug effects
Mixed Function Oxygenases--antagonists & inhibitors
NADPH-Ferrihemoprotein Reductase--analysis
Organothiophosphorus Compounds--toxicity
Phenobarbital--pharmacology
Proadifen--pharmacology
Rats
Rats, Inbred Strains
Structure-Activity Relationship
Effects of alkyl phosphorothioates on the hepatic microsomal mixed-function oxidase system in rats. Inhibition of drug-metabolizing enzyme activity and selective increase of NADPH-cytochrome c reductase activity. [electronic resource] - Biochemical pharmacology Mar 1986 - 1019-26 p. digital
Publication Type: Journal Article
0006-2952
10.1016/0006-2952(86)90093-6 doi
Animals
Cholinesterase Inhibitors--toxicity
Dose-Response Relationship, Drug
Male
Methylcholanthrene--pharmacology
Microsomes, Liver--drug effects
Mixed Function Oxygenases--antagonists & inhibitors
NADPH-Ferrihemoprotein Reductase--analysis
Organothiophosphorus Compounds--toxicity
Phenobarbital--pharmacology
Proadifen--pharmacology
Rats
Rats, Inbred Strains
Structure-Activity Relationship