Towards development of a statistical framework to evaluate myotonic dystrophy type 1 mRNA biomarkers in the context of a clinical trial.

Kurkiewicz, Adam

Towards development of a statistical framework to evaluate myotonic dystrophy type 1 mRNA biomarkers in the context of a clinical trial. [electronic resource] - PloS one 2020 - e0231000 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0231000 doi


Alternative Splicing
Biostatistics
Clinical Trials as Topic--methods
Databases, Nucleic Acid--statistics & numerical data
Genetic Markers
Humans
Least-Squares Analysis
Machine Learning
Models, Genetic
Muscles--metabolism
Myotonic Dystrophy--genetics
Myotonin-Protein Kinase--genetics
Oligonucleotide Array Sequence Analysis--statistics & numerical data
Polyadenylation
RNA, Messenger--genetics
Treatment Outcome
Trinucleotide Repeat Expansion