Characterization of therapy-related acute leukemia in hereditary breast-ovarian carcinoma patients: role of BRCA1 mutation and topoisomerase II-directed therapy.

Bagal, Bhausaheb

Characterization of therapy-related acute leukemia in hereditary breast-ovarian carcinoma patients: role of BRCA1 mutation and topoisomerase II-directed therapy. [electronic resource] - Medical oncology (Northwood, London, England) Apr 2020 - 48 p. digital

Publication Type: Case Reports; Journal Article

1559-131X

10.1007/s12032-020-01371-z doi


Adult
Antineoplastic Combined Chemotherapy Protocols--adverse effects
BRCA1 Protein--genetics
Carcinoma--drug therapy
Female
Germ-Line Mutation
Hereditary Breast and Ovarian Cancer Syndrome--drug therapy
Humans
Leukemia, Myeloid, Acute--chemically induced
Middle Aged
Oncogene Proteins, Fusion--genetics
Topoisomerase II Inhibitors--adverse effects
Translocation, Genetic
Treatment Outcome