Composition and Orientation of the Core Region of Novel HIV-1 Entry Inhibitors Influences Metabolic Stability.

Karadsheh, Rama

Composition and Orientation of the Core Region of Novel HIV-1 Entry Inhibitors Influences Metabolic Stability. [electronic resource] - Molecules (Basel, Switzerland) Mar 2020

Publication Type: Journal Article

1420-3049

10.3390/molecules25061430 doi


Anti-HIV Agents--pharmacology
Azabicyclo Compounds--chemical synthesis
Azetidines--chemical synthesis
Chromatography, Liquid
HEK293 Cells
HIV Core Protein p24--chemistry
HIV Fusion Inhibitors--metabolism
HIV Infections--drug therapy
HIV-1--drug effects
Humans
Microsomes, Liver--virology
Organophosphates--chemistry
Piperazines--chemistry
Protein Binding
Pyrrolidines--chemical synthesis
Tandem Mass Spectrometry
Triazoles--chemical synthesis